Dawn Hsiao-Wei Loh
Dawn Loh majored in Genetics at the University of Edinburgh, and obtained her PhD in Molecular Genetics at the Medical Research Council Human Genetics Unit. She received postdoctoral training in Neuroscience; first with Anthony Harmar at the University of Edinburgh, then with James Waschek and Christopher Colwell at the University of California – Los Angeles (UCLA). Dawn is interested in the interaction between circadian rhythms and neurological diseases. She currently studies the impact of circadian and sleep/wake rhythm disruption on disease progression in animal models of Huntington’s disease (HD) and Autism Spectrum Disorders (ASD). Her overarching hypothesis is that circadian and sleep/wake rhythm disruption is a disease modifier, and that treatment of circadian rhythm disruption may have beneficial effects on disease progression and symptoms.
Dawn is bridging the gap between pre-clinical models and the patient population by collaborating with the UCLA HDSA Center of Excellence, examining circadian and sleep/wake rhythms of HD patients and caregivers. An overview of the study can be seen at the Huntington'd Disease Society of America's HD Research Webinar Series: At home monitoring of sleep/wake cycles in Huntington's disease patients. If you are interested in participating in HD sleep/wake rhythm research studies, please contact Dawn at