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Publications |
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2008 |
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Coskun V, Wu H, Blanchi B, Kim KJ, Tao S, Biancotti JC, Hutnick L, Kruger R, Fan G, deVellis J, Sun YE. CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. PNAS, 2008, 105(3):1026-31 Hamby, M., Coskun, V., Sun, Y.E. The true complexity of transcriptional regulation of neuronal differentiation: epigenetic influences. Biochimica et Biophysica Acta 2008 Aug;1779(8):432-7. Epub 2008 Jul 28. Gray M, Shirasaki D, Cepeda C, Wilburn B, Tao J, Li S, Sun YE, Li X, Levine MS, Yang XW, BACHD Mice Recapitulate Phenotypic Features of Adult-onset HD without Overt Striatal Nuclear Translocation and Accumulation of Mutant Huntingtin. J. Neurosci. 2008, 28(24):6182-95 Wu H, Kim K, Mehta K, Paxia X, Sundstrom A, Anantharaman T, Kuraishy A, Doan T, Ghosh J, Pyle A, Clark A, Lowry W, Fan G, Baxter T, Mishra B, Sun Y, Teitell M. Copy number variant analysis of human embryonic stem cells. Stem Cells, 2008, 26(6):1484-9 |
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2007 |
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Coskun, V., Zhao, J. and Sun, Y.E. Neurons or glia? Can SHP2 know it all? Science STKE, 2007 (410): pe58 Bredy TW, Wu H, Crego C, Zellhoefer J, Sun YE, Barad M. Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learning and Memory, 2007 14(4): 268-76 Zhang C, Ng KL, Li JD, He F, Anderson DJ, Sun YE, Zhou QY. Prokineticine 2 is a target gene of proneural basic helix-loop-helix factors for olfactory bulb neurogenesis. Journal of Biological Chemistry, 2007 282(10): 6917-21 Khidekel N, Ficarro SB, Clark PM, Bryan MC, Swaney DL, Rexach JE, Sun YE, Coon JJ, Peters EC and Hsieh-Wilson LC. Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics. Nature Chemical Biology, 2007 3(6): 339 – 348 Saxe J, Wu H, Kelly TK, Phelps M, Sun YE* (co-corresponding), Kornblum H, Huang J. A phenotypic small molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. Chemistry & Biology, 2007 14(9): 1019-30 Wu H, Xu J, Pang Z, Ge W, Blanchi B, Kim KJ, Chen C, Südhof TC, Sun YE. Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. PNAS, 2007 104(34):13821-6 |
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Ge W, He F, Kim KJ, Blanchi B, Coskun V, Nguyen, L, Wu X, Zhao J, Heng J, Martinowich K, Tao J, Wu H, Castro D, Sobeih MM, Corfas G, Gleeson JG, Greenberg ME, Guillemot F, Sun YE. Coupling of Cell Migration with Neurogenesis by Proneural bHLH Factors. PNAS, 2006 103(5) 1319-24 Kruger RC Jr.,Wu H, Zandian M, Danielpour M, Kabos P, Yu JS, Sun YE. Neural progenitors populate the cerebrospinal fluid of preterm patients with hydrocephalus. Journal of Pediatrics, 2006 148(3) 337-340 Wu H, Sun YE. Epigenetic Regulation of Stem Cell Differentiation. Pediatric Research, 2006 59(4 pt2): 21R-5R Wu H, Sun YE. The ups and downs of BDNF in Rett Syndrome. Neuron, 2006 49(3): 321-323 |
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2006 |
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He, F., Ge, W., Zhu, W., Becker-Catania, S., Martinowich, K., Wu, H., Coskun, V., Fan, G., deVellis, J., Sun, YE. positive autoregulation loop of JAK-STAT signaling is part of the clock mechanism regulating astrogliogenesis. Nature Neuroscience, 2005 8(5) 616-625 Fan G, Martinowich K, Chin M, He F, Fouse S, Hattori D, Ge W, tenHovee J, Shai K, Sun YE. DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development, 2005 132(15): 3345-56. Ladi E, Nichols JT, Ge W, Miyamoto A, Yao C, Yang LT, Boulter J, Sun YE, Kinter C, Weinmaster G. The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands. Journal of Cell Biology, 2005 170(6) 983-992 Damelin M, Sun YE, Sodja VB, Bestor T. Decatenation Checkpoint Deficiency in Stem and Progenitor Cells. Cancer Cell, 2005 8(6): 479-484 |
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2005 |
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Martin KC, Sun YE. To Learn Better, Keep the HAT on. Neuron, 2004 879-881 |
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2004 |
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Ge W, Martinowich K, Wu X, He F,Miyamoto A, Fan G, Weinmaster G, Sun YE. Notch signaling promotes astrogliogenesis via direct CSL-mediated glial gene activation. Journal of Neuroscience Research, 2002 69: 848-860 |
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2002 |
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Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y, Fan G, Sun YE. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation, Science, 2003 302:890-3. Sun YE, Martinowich K, Ge W. Making and repairing the mammalian brain-signaling toward neurogenesis and gliogenesis. Seminars in Cell & Developmental Biology, 2003 375: 1-8 |
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2003 |
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2009 |
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Tao, J, Hu, K, Chang, Q, Wu, H, Sherman, NE, Martinowich, K, Klose, RJ, Schanen, C, Jaenisch, R, Wang, W, Sun, YE. Phosphorylation of MeCP2 at serine 80 regulates its chromatin association and neurological function. PNAS, 2009 Mar 24;106(12):4882-7. Epub 2009 Feb 18 Goff, LA, Davila, J, Swerdel, MR, Moore, JC, Cohen, RI, Wu, H, Sun, YE, Hart, RP, Ago2 Immunoprecipitation identified predicted microRNAs in human embryonic stem cells and precursors. PloSOne 2009; 4(9):e7192 Tao, J, Wu, H, Sun, YE, Deciphering Rett Syndrome with Mouse Genetics, Epigenomics, and human neurons. Book Chapter, IRN (Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders) 2009; 89:147-60 |
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2010 |
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Wu, H, Tao, J, Chen, PJ, Shahab, A, Ge, W, Hart, RP, Ruan, X, Ruan, Y, Sun, YE, Systematic screening identifies microRNAs dys-regulated in a mouse model of Rett syndrome. PNAS 2010 107(42):18161-6. Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, Sun YE. Dnmt3a-dependent non-promoter DNA methylation facilitates transcription of neurogenic genes. Science, 2010, Vol. 329. no. 5990, pp. 444-448. Rexach, JE, Rogers, CJ, Yu, SH, Tao, J, Sun, YE, Hsieh-Wilson, LC, Quantification of O-Glycosylation Stoichiometry and Dynamics using Resolvable Mass Tags. Nature Chemistry and Biology 2010; 6(9):634-5 Wu, H, Sun, YE. Reversing DNA Methylation: New Insights from Neuronal Activity-Induced Gadd45b in Adult Neurogenesis. Science Signaling 2010; 2(64):pe17 Bredy TW, Sun YE, Kobor MS. How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol. 2010 Feb 2. Jang, SW, Liu, X, Yepes, M, Shepherd, KR, Miller, GW, Liu, Y, Wilson, WD, LeBlanc, A, Xiao, G, Blanchi, B, Sun, YE, and Ye, K. A Selective TrkB Agonist with Potent Neurotrophic Activities by a Natural Product 7,8-dihydroxyflavone. PNAS, 2010 Feb 9;107(6):2687-92.
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2011 |
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Li, G, Ruan, X, Auerbach, R, Sandhu, KS, Zheng, M, Wang, P, Poh, HM, Goh, Y, Lim, J, Zhang, J, Sim, HS, Peh, SQ, Mulawadi, FH, Ong, CT, Orlov, YL, Hong, S, Zhang, Z, Landt, S, Raha, D, Euskirchen, G, Wei, CL, Ge, W, Wang, H, Davis, C, Fisher-Aylor, KI, Mortazavi, A, Gerstein, M, Gingeras, T, Wold, B, Sun, Y, Fullwood, M, Cheung, E, Liu, E, Sung, WK, Snyder, M, Ruan, Y. Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation. Cell 2012 Jan. 20; 148 (1–2); 84–98. Coskun, V., Tsoa, R., Sun, Y.E., Epigenetic regulation of stem cells differentiating along neural lineage. Current Opinion in Neurobiology 2012, Oct;22(5):762-7 |
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2012 |
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Wu, H, D’Alessio, AC, Ito, S, Xia, K, Wang, Z, Cui, K, Zhao, K, Sun, Y, and Zhang, Y, Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 2011 Mar 30 Wu, H, D’Alessio, AC, Ito, S, Wang, Z, Cui , K, Zhao, K, Sun, YE, and Zhang, Y, Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes & Dev. 2011 Apr 1;25(7):679-84. Tao, J, Wu, H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE, Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. J Neurosci. 2011 Jun 1;31(22):8306-19 Lin, Q, Wei, W, Coelho CM, Li X, Baker-Andresen D, Dudley K, Ratnu VS, Boskovic Z, Kobor MS, Sun YE, Bredy TW. The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nature Neuroscience 2011;14(9):1115-7 |